GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UCEC | cis | rs763014 | 1 | rs7205409 | chr16:642610 | WFIKKN1 | chr16:679239-684116:+ | 0.35 | 4.43 | 1.83E-5 | Height |
| UCEC | cis | rs9894429 | 1 | rs7209180 | chr17:79581519 | TSPAN10 | chr17:79609349-79615778:+ | 0.66 | 8.57 | 1.11E-14 | Eye color traits |
| UCEC | cis | rs9894429 | 1 | rs7213129 | chr17:79581573 | TSPAN10 | chr17:79609349-79615778:+ | 0.66 | 8.57 | 1.11E-14 | Eye color traits |
| UCEC | cis | rs9894429 | 1 | rs7222241 | chr17:79574714 | TSPAN10 | chr17:79609349-79615778:+ | 0.69 | 8.93 | 1.32E-15 | Eye color traits |
| UCEC | cis | rs9894429 | 1 | rs7223613 | chr17:79574803 | TSPAN10 | chr17:79609349-79615778:+ | -0.66 | -8.57 | 1.11E-14 | Eye color traits |
| UCEC | cis | rs12220777 | 1 | rs72644213 | chr10:81783660 | LOC219347 | chr10:81805991-81838949:- | 0.6 | 4.52 | 1.21E-5 | Chronic obstructive pulmonary disease-related biomarkers |
| UCEC | cis | rs9815354 | 1 | rs73069394 | chr3:41787233 | ULK4 | chr3:41288091-42003660:- | 0.55 | 6.59 | 6.75E-10 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs73069396 | chr3:41787236 | ULK4 | chr3:41288091-42003660:- | 0.55 | 6.59 | 6.75E-10 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs73071329 | chr3:41810539 | ULK4 | chr3:41288091-42003660:- | 0.51 | 5.86 | 2.71E-8 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs73077367 | chr3:41851959 | ULK4 | chr3:41288091-42003660:- | 0.51 | 5.97 | 1.63E-8 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs73079321 | chr3:41863910 | ULK4 | chr3:41288091-42003660:- | 0.45 | 5.21 | 6.13E-7 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs73081353 | chr3:41906448 | ULK4 | chr3:41288091-42003660:- | 0.43 | 4.44 | 1.7E-5 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs73081364 | chr3:41913616 | ULK4 | chr3:41288091-42003660:- | 0.43 | 4.44 | 1.7E-5 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs7356093 | chr3:134238753 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.65 | 7.29E-6 | Height |
| UCEC | cis | rs10935120 | 1 | rs7371896 | chr3:134249769 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.62 | 8.08E-6 | Height |